Cancer Care Inequities: Social Determinants, Diagnostic Delays, and Health-System Strategies for Equitable Access

Autores/as

DOI:

https://doi.org/10.64784/312

Palabras clave:

cancer inequities, oncology access, social determinants of health, cancer diagnosis, treatment delay, health disparities, financial toxicity, geographic barriers, patient navigation, health systems, cancer care, health equity

Resumen

Inequities in access to cancer diagnosis and treatment remain a major challenge for contemporary health systems, particularly among populations affected by socioeconomic disadvantage, financial vulnerability, geographic isolation, limited health literacy, and fragmented healthcare pathways. This study analyzed the interaction between social determinants of health and structural characteristics of healthcare systems that influence timely access to oncology services. A documentary, integrative, descriptive, and analytical review was conducted using the Scientific Method as the methodological framework. Scientific evidence from international settings, Latin America, and Mexico was examined and organized according to socioeconomic, geographic, financial, organizational, and healthcare-process determinants. The results showed that socioeconomic factors were the most frequently represented dimension in the reviewed literature, followed closely by organizational and health-system barriers. Diagnostic evaluation was identified as the stage of the cancer-care continuum in which access barriers were most frequently documented, followed by treatment initiation and continuity of care. Referral fragmentation, prolonged waiting times, insufficient specialist availability, financial barriers, geographic concentration of services, and diagnostic infrastructure limitations were recurrent findings. Evidence from Mexico demonstrated that substantial delays may occur after patients have already entered the healthcare system, emphasizing that formal coverage does not necessarily guarantee effective access. The most frequently identified health-system strategies included integrated care pathways, rapid referral and diagnostic mechanisms, strengthening of diagnostic capacity, financial protection, decentralization of selected services, and patient navigation. The findings support the hypothesis that cancer-care inequities arise from the cumulative interaction of social vulnerability and modifiable health-system barriers. Reducing these disparities requires coordinated, multilevel interventions capable of improving diagnostic timeliness, treatment initiation, continuity of care, geographic accessibility, and financial protection. Equity in oncology should therefore be understood as the capacity of health systems to provide timely, continuous, affordable, and appropriate care according to clinical need rather than socioeconomic position, place of residence, or financial capacity.

Referencias

• Gironés Sarrió, R., Benítez Fuentes, J. D., García Samblás, V., Guillot Morales, M., Palacios Ozores, P., Ruiz-Casado, A., Torres-Jiménez, J., & Vieito Villar, M. (2026). Impact of social determinants on the development, diagnosis, and treatment of cancer: Recommended public health interventions. Clinical and Translational Oncology, 28(6), 2041–2055. https://doi.org/10.1007/s12094-025-04129-z

• Syrnioti, G., Eden, C. M., Johnson, J. A., Alston, C., Syrnioti, A., & Newman, L. A. (2023). Social determinants of cancer disparities. Annals of Surgical Oncology, 30(13), 8094–8104. https://doi.org/10.1245/s10434-023-14200-0

• Alcaraz, K. I., Wiedt, T. L., Daniels, E. C., Yabroff, K. R., Guerra, C. E., & Wender, R. C. (2020). Understanding and addressing social determinants to advance cancer health equity in the United States: A blueprint for practice, research, and policy. CA: A Cancer Journal for Clinicians, 70(1), 31–46. https://doi.org/10.3322/caac.21586

• Beltrán Ponce, S. E., Thomas, C. R., & Diaz, D. A. (2022). Social determinants of health, workforce diversity, and financial toxicity: A review of disparities in cancer care. Current Problems in Cancer, 46(5), 100893. https://doi.org/10.1016/j.currproblcancer.2022.100893

• Freeman, H. P., & Chu, K. C. (2005). Determinants of cancer disparities: Barriers to cancer screening, diagnosis, and treatment. Surgical Oncology Clinics of North America, 14(4), 655–669. https://doi.org/10.1016/j.soc.2005.06.002

• Ward, E., Jemal, A., Cokkinides, V., Singh, G. K., Cardinez, C., Ghafoor, A., & Thun, M. (2004). Cancer disparities by race/ethnicity and socioeconomic status. CA: A Cancer Journal for Clinicians, 54(2), 78–93. https://doi.org/10.3322/canjclin.54.2.78

• Rodday, A. M., Parsons, S. K., Snyder, F., Simon, M. A., Llanos, A. A. M., Warren-Mears, V., Dudley, D., Lee, J.-H., Patierno, S. R., Markossian, T. W., Sanders, M., Whitley, E. M., & Freund, K. M. (2015). Impact of patient navigation in eliminating economic disparities in cancer care. Cancer, 121(22), 4025–4034. https://doi.org/10.1002/cncr.29612

• Bright, K., Barghash, M., Donach, M., Gutiérrez de la Barrera, M., Schneider, R. J., & Formenti, S. C. (2011). The role of health system factors in delaying final diagnosis and treatment of breast cancer in Mexico City, Mexico. The Breast, 20(Suppl. 2), S54–S59. https://doi.org/10.1016/j.breast.2011.02.012

• Unger-Saldaña, K., Ventosa-Santaulària, D., Miranda, A., & Verduzco-Bustos, G. (2018). Barriers and explanatory mechanisms of delays in the patient and diagnosis intervals of care for breast cancer in Mexico. The Oncologist, 23(4), 440–453. https://doi.org/10.1634/theoncologist.2017-0431

• Zapata-Tarrés, M., González-Domínguez, E., Doubova, S. V., Menendez-Auld, N., Cruz-Medina, C. S., Gonzalez-Ramella, R. O., Vega-Vega, L., Guevara-Espejel, C., Juárez-Villegas, L., & Pérez-Cuevas, R. (2020). Patient and health service factors associated with delays in cancer treatment for children without social security in Mexico. Pediatric Blood & Cancer, 67(9), e28331. https://doi.org/10.1002/pbc.28331

• Longo, C. J., & Fitch, M. I. (2021). Unequal distribution of financial toxicity among people with cancer and its impact on access to care: A rapid review. Current Opinion in Supportive and Palliative Care, 15(3), 157–161. https://doi.org/10.1097/SPC.0000000000000561

• Nepal, P., Zafar, M. H., Liu, L. C., Xu, Z., Abdulhai, M. A., Perez-Tamayo, A. M., Chaudhry, V., Mellgren, A. F., & Gantt, G. A. (2024). Socioeconomic disparities in anal cancer: Effect on treatment delay and survival. Diseases of the Colon & Rectum, 67(6), 773–781. https://doi.org/10.1097/DCR.0000000000003184

• Knight, T. G., Deal, A. M., Dusetzina, S. B., Muss, H. B., Choi, S. K., Bensen, J. T., & Williams, G. R. (2018). Financial toxicity in adults with cancer: Adverse outcomes and noncompliance. Journal of Oncology Practice, 14(11), e665–e673. https://doi.org/10.1200/JOP.18.00120

• Farmer, P., Frenk, J., Knaul, F. M., Shulman, L. N., Alleyne, G., Armstrong, L., Atun, R., Blayney, D., Chen, L., Feachem, R., Gospodarowicz, M., Gralow, J., Gupta, S., Langer, A., Lob-Levyt, J., Neal, C., Mbewu, A., Mired, D., Piot, P., … Seffrin, J. R. (2010). Expansion of cancer care and control in countries of low and middle income: A call to action. The Lancet, 376(9747), 1186–1193. https://doi.org/10.1016/S0140-6736(10)61152-X

• Goss, P. E., Lee, B. L., Badovinac-Crnjevic, T., Strasser-Weippl, K., Chavarri-Guerra, Y., St Louis, J., Villarreal-Garza, C., Unger-Saldaña, K., Ferreyra, M., Debiasi, M., Liedke, P. E. R., Touya, D., Werutsky, G., Higgins, M., Fan, L., Vasconcelos, C., Cazap, E., Vallejos, C., Mohar, A., … Azenha, G. (2013). Planning cancer control in Latin America and the Caribbean. The Lancet Oncology, 14(5), 391–436. https://doi.org/10.1016/S1470-2045(13)70048-2

• Abdullah, A., Liu, Z., & Molinari, M. (2025). From diagnosis to survivorship: The role of social determinants in cancer care. Cancers, 17(7), 1067. https://doi.org/10.3390/cancers17071067

• Islami, F., Baeker Bispo, J., Lee, H., Wiese, D., Yabroff, K. R., Bandi, P., Sloan, K., Patel, A. V., Daniels, E. C., Kamal, A. H., Guerra, C. E., Dahut, W. L., & Jemal, A. (2024). American Cancer Society’s report on the status of cancer disparities in the United States, 2023. CA: A Cancer Journal for Clinicians, 74(2), 136–166. https://doi.org/10.3322/caac.21812

• Srivastav, A. K., Singh, A., Singh, S., Rivers, B., Lillard, J. W., Jr., & Singh, R. (2025). Revolutionizing oncology through AI: Addressing cancer disparities by improving screening, treatment, and survival outcomes via integration of social determinants of health. Cancers, 17(17), 2866. https://doi.org/10.3390/cancers17172866

• Abbott, D. E., Voils, C. L., Fisher, D. A., Greenberg, C. C., & Safdar, N. (2017). Socioeconomic disparities, financial toxicity, and opportunities for enhanced system efficiencies for patients with cancer. Journal of Surgical Oncology, 115(3), 250–256. https://doi.org/10.1002/jso.24528

• Sheni, R., Qin, J., Viswanathan, S., Castellucci, E., Kalnicki, S., & Mehta, V. (2023). Predictive factors for cancer treatment delay in a racially diverse and socioeconomically disadvantaged urban population. JCO Oncology Practice, 19(6), e904–e915. https://doi.org/10.1200/OP.22.00779

Publicado

2026-09-02

Cómo citar

Cancer Care Inequities: Social Determinants, Diagnostic Delays, and Health-System Strategies for Equitable Access (Andrés Omar Triviño Pinto, Lisset Georgett Saldaña Cortés, José Arnulfo Pérez Carrillo, Blas David Santana Perez, Aldo Bolivar Zavala Segovia, María Fernanda Carbajal Hernández, Jorge Angel Velasco Espinal, & Alexa Fernanda Uriostegui Navarro, Trans.). (2026). IECCMEXICO, 5(2). https://doi.org/10.64784/312